Acute Lymphoblastic Leukemia (ALL)

Acute lymphocytic leukemia (ALL) is also called acute lymphoblastic leukemia. The term acute means that the leukemia grows quickly, and if not treated, could be fatal in a few months. People with chronic leukemia can live years without treatment. Lymphocytic means it develops from early forms of lymphocytes, a type of white blood cell. This is different from acute myeloid leukemia (AML), which starts in other blood cell types found in the bone marrow. Neoplastic disease which results from a mutation in a single lymphoid progenitor cell at one of several discrete stages of development in B cell or T cell.


Risk factors of ALL

There are only a few known risk factors for ALL.

Signs and Symptoms of ALL



Immunologic Subtype % of cases FAB Subtype Cytogenetic Abnormalities
Pre-B ALL 75 L1, L2 t(9;22), t(4;11), t(1;19)
T cell ALL 20 L1, L2 14q11 or 7q34
B cell ALL 5 L3 t(8;14), t(8;22), t(2;8)


Relapse and Prognosis